CHANGELOG
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v 1.1 beta, January 2021
The first uses of RNAnet by people from outside the development team happened between this December.
A few feedback allowed to identify issues and useful information to add.
FEATURE CHANGES
- Sequence alignments of the 3D structures mapped to a family are now provided.
- Full alignements with Rfam sequences are not provided, but you can ask us for the files.
- Two new fields in table 'family': ali_length and ali_filtered_length.
They are the MSA lengths of the alignment with and without the Rfam sequences.
TECHNICAL CHANGES
- SQLite connexions are now all in WAL mode by default (previously, only the writers used WAL mode)
BUG CORRECTIONS
- When an alignment file is updated in a newer run of RNANet, all the re_mappings are now re-computed
for this family. Previously, the remappings were computed only for the newly added sequences,
while the alignment actually changed even for chains added in past runs.
- Changed the ownership and permissions of files produced by the Docker container.
They were previously owned by root and the user could not get access to them.
- Modified nucleotides were not always correctly transformed to N in the alignments (and nucleotide.nt_align_code fields).
Now, the alignments and nt_align_code only contain "ACGUN-" chars.
Now, 'N' means 'other', while '-' means 'nothing'.
COMING SOON
- Automated annotation of detected Recurrent Interaction Networks (RINs), see http://carnaval.lri.fr/ .
- Possibly, automated detection of HLs and ILs from the 3D Motif Atlas (BGSU). Maybe. Their own website already does the job.
- A field estimating the quality of the sequence alignment in table family.
- Possibly, more metrics about the alignments coming from Infernal.