// These parameter values are extracted from the larger files rna1995.dG 
// Serra and Turner, 1995 
// >All values represent delta G in units of decacal/mol (0.01 kcal/mol)

struct sp_loops {
    const char* s;
    int         e;
};

static sp_loops triloops[] = {{"AAAAU", 0}, {nullptr, 0}};

static sp_loops tetraloops[] = {
{"AAUUUU", -200}, 
{"ACUUGU", -200}, 
{"AGAAAU", -200}, 
{"AGAGAU", -200}, 
{"AGCAAU", -200}, 
{"AGCGAU", -200}, 
{"AGGAAU", -200}, 
{"AGUAAU", -200}, 
{"AGUGAU", -200}, 
{"AUACGU", -200}, 
{"AUCCGU", -200}, 
{"AUUCGU", -200}, 
{"AUUUAU", -200}, 
{"CAUUUG", -200}, 
{"CCUUGG", -200}, 
{"CGAAAG", -200}, 
{"CGAGAG", -200}, 
{"CGCAAG", -200}, 
{"CGCGAG", -200}, 
{"CGGAAG", -200}, 
{"CGUAAG", -200}, 
{"CGUGAG", -200}, 
{"CUACGG", -200}, 
{"CUCCGG", -200}, 
{"CUUCGG", -200}, 
{"CUUUAG", -200}, 
{"GAUUUC", -200}, 
{"GAUUUU", -200}, 
{"GCUUGC", -200}, 
{"GCUUGU", -200}, 
{"GGAAAC", -200}, 
{"GGAAAU", -200}, 
{"GGAGAC", -200}, 
{"GGAGAU", -200}, 
{"GGCAAC", -200}, 
{"GGCAAU", -200}, 
{"GGCGAC", -200}, 
{"GGCGAU", -200}, 
{"GGGAAC", -200}, 
{"GGGAAU", -200}, 
{"GGUAAC", -200}, 
{"GGUAAU", -200}, 
{"GGUGAC", -200}, 
{"GGUGAU", -200}, 
{"GUACGC", -200}, 
{"GUACGU", -200}, 
{"GUCCGC", -200}, 
{"GUCCGU", -200}, 
{"GUUCGC", -200}, 
{"GUUCGU", -200}, 
{"GUUUAC", -200}, 
{"GUUUAU", -200}, 
{"UAUUUA", -200}, 
{"UAUUUG", -200}, 
{"UCUUGA", -200}, 
{"UCUUGG", -200}, 
{"UGAAAA", -200}, 
{"UGAAAG", -200}, 
{"UGAGAA", -200}, 
{"UGAGAG", -200}, 
{"UGCAAA", -200}, 
{"UGCAAG", -200}, 
{"UGCGAA", -200}, 
{"UGCGAG", -200}, 
{"UGGAAA", -200}, 
{"UGGAAG", -200}, 
{"UGUAAA", -200}, 
{"UGUAAG", -200}, 
{"UGUGAA", -200}, 
{"UGUGAG", -200}, 
{"UUACGA", -200}, 
{"UUACGG", -200}, 
{"UUCCGA", -200}, 
{"UUCCGG", -200}, 
{"UUUCGA", -200}, 
{"UUUCGG", -200}, 
{"UUUUAA", -200}, 
{"UUUUAG", -200}, 
{nullptr, 0}};

static int thermo_params[] = {
// >Stacking 5' X1 Y1 3'
// >         3' X2 Y2 5'
// >X1X2 = AU CG GC UA GU UG (row headings)
// >Y1Y2 = AU CG GC UA GU UG (column headings)
-90, -210, -170, -90, -50, -100, 
-180, -290, -200, -170, -120, -190, 
-230, -340, -290, -210, -140, -210, 
-110, -230, -180, -90, -80, -110, 
-110, -210, -190, -100, -40, 150, 
-80, -140, -120, -50, -20, -40, 
// >Hairpin Loop Energies: size = 1,2,3,..,30
0, 0, 410, 490, 440, 470, 500, 510, 520, 530, 540, 550, 560, 570, 580, 580, 590, 590, 600, 610, 610, 620, 620, 630, 630, 630, 640, 640, 650, 650, 
 // >Bulge loop Energies: size = 1,2,3,..,30
390, 310, 350, 420, 480, 500, 520, 530, 540, 550, 570, 570, 580, 590, 600, 610, 610, 620, 620, 630, 630, 640, 640, 650, 650, 650, 660, 670, 670, 670, 
 // >Interior Loop Energies: size = 1,2,3,..,30
0, 410, 510, 490, 530, 570, 590, 600, 610, 630, 640, 640, 650, 660, 670, 680, 680, 690, 690, 700, 710, 710, 710, 720, 720, 730, 730, 740, 740, 740, 
// >NINIO asymmetry Terms: m1, m2, m3, m4, max
// >Energy = MAX[ max, asymmetry*m#] where # = MIN(4,L1,L2)
// >and L1, L2 are lengths of each side of loop, 
// >and asymmetry = |L1-L2|
30, 30, 30, 30, 300, 
// >Mismatch HP:
// >Columns 5'-AU,CG,GC,UA,GU,UG-3'
// >rows 5'-AA,AC,AG,AU,CA,..,UU-3'
-80, -140, -110, -100, -80, -120, 
-100, -200, -130, -80, -100, -140, 
-170, -210, -200, -180, -170, -200, 
-100, -190, -130, -90, -100, -140, 
-70, -100, -110, -70, -70, -90, 
-70, -110, -60, -60, -70, -90, 
-70, -100, -60, -30, -70, -70, 
-70, -80, -50, -50, -70, -70, 
-150, -210, -230, -180, -150, -200, 
-100, -190, -150, -90, -100, -140, 
-100, -140, -140, -120, -100, -130, 
-100, -190, -150, -90, -100, -140, 
-80, -140, -80, -30, -80, -90, 
-80, -150, -80, -60, -80, -110, 
-80, -140, -80, -30, -80, -90, 
-80, -120, -70, -50, -80, -90, 
// >Mismatch Interior:
// >Columns 5'-AU,CG,GC,UA,GU,UG-3'
// >rows 5'-AA,AC,AG,AU,CA,..,UU-3'
-100, -150, -150, -100, -150, -100, 
-100, -150, -150, -100, -150, -100, 
-220, -270, -270, -220, -270, -220, 
-50, -190, -130, -40, -130, -40, 
-100, -150, -150, -100, -150, -100, 
-100, -150, -150, -100, -150, -100, 
-20, -100, -60, 20, -60, 20,
 -100, -150, -150, -100, -150, -100, 
 -220, -270, -270, -220, -270, -220,
  -50, -190, -150, -40, -150, -40, 
  -100, -150, -150, -100, -150, -100, 
  -50, -190, -150, -40, -150, -40, 
  -30, -140, -80, 20, -80, 20, 
  -100, -150, -150, -100, -150, -100, 
  -30, -140, -80, 20, -80, 20, 
  -200, -250, -250, -200, -250, -200, 
// >Dangle Energies: 5' X1 Y 3'
// >                 3' X2 . 5'
// >Columns: Y = A, C, G, U
// >Rows = X1X2 = AU,CG,GC,UA,GU,UG
-80, -50, -80, -60, 
-170, -80, -170, -120, 
-110, -40, -130, -60, 
-70, -10, -70, -10, 
-80, -50, -80, -60, 
-120, -50, -120, -70, 
// >Dangle Energies: 5' X1 . 3'
// >                 3' X2 Y 5'
// >Columns: Y = A, C, G, U
// >Rows = X1X2 = AU,CG,GC,UA,GU,UG
-30, -10, -20, -20, 
-20, -30, 0, 0, 
-50, -30, -20, -10, 
-30, -30, -40, -20, 
-20, -20, -20, -20, 
-20, -20, -20, -20, 
// >Multiloop terms: ALPHA_1, ALPHA_2, ALPHA_3
// >ML penalty = ALPHA_1 + s * ALPHA_2 + u *ALPHA_3
// >s = # stems adjacent to ML, u = unpaired bases in ML
460, 10, 40, 
// >AT_PENALTY:
// >Penalty for non GC pairs that terminate a helix
0, 
// >Interior Loops 1x1
// >CG..AU = 5'- C X A 3'
// >         3'- G Y U 5'
// >Rows: X = A C G U (X constant for a row)
// >Columns: Y = A C G U (Y constant in column)
// AU..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// AU..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// AU..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// AU..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// AU..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// AU..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// CG..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GC..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UA..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// GU..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..AU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..CG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..GC
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..UA
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..GU
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// UG..UG
80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 80, 
// >Interior Loops 2x2
// >CG.AG..AU = 5'- C A G A -3'
// >            3'- G Y X U -5'
// >Rows: X = A C G U (X constant for a row)
// >Columns: Y = A C G U (Y constant in column)
// AU.AA..AU
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 410, 410, 290, 460, 
// AU.AC..AU
290, 290, 170, 340, 290, 290, 170, 340, 350, 350, 230, 400, 290, 290, 170, 340, 
// AU.AG..AU
170, 170, 50, 220, 410, 410, 290, 460, 290, 290, 170, 340, 410, 410, 290, 460, 
// AU.AU..AU
350, 350, 230, 400, 290, 290, 170, 340, 350, 350, 230, 400, 190, 190, 70, 240, 
// AU.CA..AU
290, 290, 370, 290, 290, 290, 370, 290, 170, 170, 250, 170, 410, 410, 490, 410, 
// AU.CC..AU
290, 290, 370, 290, 290, 290, 370, 290, 350, 350, 430, 350, 290, 290, 370, 290, 
// AU.CG..AU
170, 170, 250, 170, 410, 410, 490, 410, 290, 290, 370, 290, 410, 410, 490, 410, 
// AU.CU..AU
350, 350, 430, 350, 290, 290, 370, 290, 350, 350, 430, 350, 190, 190, 270, 190, 
// AU.GA..AU
170, 340, 290, 340, 170, 340, 290, 340, 50, 220, 170, 220, 290, 460, 410, 460, 
// AU.GC..AU
170, 340, 290, 340, 170, 340, 290, 340, 230, 400, 350, 400, 170, 340, 290, 340, 
// AU.GG..AU
50, 220, 170, 220, 290, 460, 410, 460, 170, 340, 290, 340, 290, 460, 410, 460, 
// AU.GU..AU
230, 400, 350, 400, 170, 340, 290, 340, 230, 400, 350, 400, 70, 240, 190, 240, 
// AU.UA..AU
360, 290, 360, 190, 360, 290, 360, 190, 240, 170, 240, 70, 480, 410, 480, 310, 
// AU.UC..AU
360, 290, 360, 190, 360, 290, 360, 190, 420, 350, 420, 250, 360, 290, 360, 190, 
// AU.UG..AU
240, 170, 240, 70, 480, 410, 480, 310, 360, 290, 360, 190, 480, 410, 480, 310, 
// AU.UU..AU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// AU.AA..CG
240, 240, 120, 290, 240, 240, 120, 290, 120, 120, 0, 170, 310, 310, 190, 360, 
// AU.AC..CG
240, 240, 120, 290, 240, 240, 120, 290, 240, 240, 120, 290, 240, 240, 120, 290, 
// AU.AG..CG
120, 120, 0, 170, 330, 330, 210, 380, 240, 240, 120, 290, 310, 310, 190, 360, 
// AU.AU..CG
260, 260, 140, 310, 240, 240, 120, 290, 240, 240, 120, 290, 140, 140, 20, 190, 
// AU.CA..CG
240, 240, 320, 240, 240, 240, 320, 240, 120, 120, 200, 120, 310, 310, 390, 310, 
// AU.CC..CG
240, 240, 320, 240, 240, 240, 320, 240, 240, 240, 320, 240, 240, 240, 320, 240, 
// AU.CG..CG
120, 120, 200, 120, 330, 330, 410, 330, 240, 240, 320, 240, 310, 310, 390, 310, 
// AU.CU..CG
260, 260, 340, 260, 240, 240, 320, 240, 240, 240, 320, 240, 140, 140, 220, 140, 
// AU.GA..CG
120, 290, 240, 290, 120, 290, 240, 290, 0, 170, 120, 170, 190, 360, 310, 360, 
// AU.GC..CG
120, 290, 240, 290, 120, 290, 240, 290, 120, 290, 240, 290, 120, 290, 240, 290, 
// AU.GG..CG
0, 170, 120, 170, 210, 380, 330, 380, 120, 290, 240, 290, 190, 360, 310, 360, 
// AU.GU..CG
140, 310, 260, 310, 120, 290, 240, 290, 120, 290, 240, 290, 20, 190, 140, 190, 
// AU.UA..CG
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 380, 310, 380, 210, 
// AU.UC..CG
310, 240, 310, 140, 310, 240, 310, 140, 310, 240, 310, 140, 310, 240, 310, 140, 
// AU.UG..CG
190, 120, 190, 20, 400, 330, 400, 230, 310, 240, 310, 140, 380, 310, 380, 210, 
// AU.UU..CG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// AU.AA..GC
240, 240, 120, 290, 240, 240, 120, 290, 120, 120, 0, 170, 250, 250, 130, 300, 
// AU.AC..GC
240, 240, 120, 290, 240, 240, 120, 290, 200, 200, 80, 250, 240, 240, 120, 290, 
// AU.AG..GC
120, 120, 0, 170, 290, 290, 170, 340, 240, 240, 120, 290, 250, 250, 130, 300, 
// AU.AU..GC
200, 200, 80, 250, 240, 240, 120, 290, 200, 200, 80, 250, 140, 140, 20, 190, 
// AU.CA..GC
240, 240, 320, 240, 240, 240, 320, 240, 120, 120, 200, 120, 250, 250, 330, 250, 
// AU.CC..GC
240, 240, 320, 240, 240, 240, 320, 240, 200, 200, 280, 200, 240, 240, 320, 240, 
// AU.CG..GC
120, 120, 200, 120, 290, 290, 370, 290, 240, 240, 320, 240, 250, 250, 330, 250, 
// AU.CU..GC
200, 200, 280, 200, 240, 240, 320, 240, 200, 200, 280, 200, 140, 140, 220, 140, 
// AU.GA..GC
120, 290, 240, 290, 120, 290, 240, 290, 0, 170, 120, 170, 130, 300, 250, 300, 
// AU.GC..GC
120, 290, 240, 290, 120, 290, 240, 290, 80, 250, 200, 250, 120, 290, 240, 290, 
// AU.GG..GC
0, 170, 120, 170, 170, 340, 290, 340, 120, 290, 240, 290, 130, 300, 250, 300, 
// AU.GU..GC
80, 250, 200, 250, 120, 290, 240, 290, 80, 250, 200, 250, 20, 190, 140, 190, 
// AU.UA..GC
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 320, 250, 320, 150, 
// AU.UC..GC
310, 240, 310, 140, 310, 240, 310, 140, 270, 200, 270, 100, 310, 240, 310, 140, 
// AU.UG..GC
190, 120, 190, 20, 360, 290, 360, 190, 310, 240, 310, 140, 320, 250, 320, 150, 
// AU.UU..GC
270, 200, 270, 100, 310, 240, 310, 140, 270, 200, 270, 100, 210, 140, 210, 40, 
// AU.AA..UA
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 360, 360, 240, 410, 
// AU.AC..UA
290, 290, 170, 340, 290, 290, 170, 340, 340, 340, 220, 390, 290, 290, 170, 340, 
// AU.AG..UA
170, 170, 50, 220, 370, 370, 250, 420, 290, 290, 170, 340, 360, 360, 240, 410, 
// AU.AU..UA
340, 340, 220, 390, 290, 290, 170, 340, 340, 340, 220, 390, 190, 190, 70, 240, 
// AU.CA..UA
290, 290, 370, 290, 290, 290, 370, 290, 170, 170, 250, 170, 360, 360, 440, 360, 
// AU.CC..UA
290, 290, 370, 290, 290, 290, 370, 290, 340, 340, 420, 340, 290, 290, 370, 290, 
// AU.CG..UA
170, 170, 250, 170, 370, 370, 450, 370, 290, 290, 370, 290, 360, 360, 440, 360, 
// AU.CU..UA
340, 340, 420, 340, 290, 290, 370, 290, 340, 340, 420, 340, 190, 190, 270, 190, 
// AU.GA..UA
170, 340, 290, 340, 170, 340, 290, 340, 50, 220, 170, 220, 240, 410, 360, 410, 
// AU.GC..UA
170, 340, 290, 340, 170, 340, 290, 340, 220, 390, 340, 390, 170, 340, 290, 340, 
// AU.GG..UA
50, 220, 170, 220, 250, 420, 370, 420, 170, 340, 290, 340, 240, 410, 360, 410, 
// AU.GU..UA
220, 390, 340, 390, 170, 340, 290, 340, 220, 390, 340, 390, 70, 240, 190, 240, 
// AU.UA..UA
360, 290, 360, 190, 360, 290, 360, 190, 240, 170, 240, 70, 430, 360, 430, 260, 
// AU.UC..UA
360, 290, 360, 190, 360, 290, 360, 190, 410, 340, 410, 240, 360, 290, 360, 190, 
// AU.UG..UA
240, 170, 240, 70, 440, 370, 440, 270, 360, 290, 360, 190, 430, 360, 430, 260, 
// AU.UU..UA
410, 340, 410, 240, 360, 290, 360, 190, 410, 340, 410, 240, 260, 190, 260, 90, 
// AU.AA..GU
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 410, 410, 290, 460, 
// AU.AC..GU
290, 290, 170, 340, 290, 290, 170, 340, 350, 350, 230, 400, 290, 290, 170, 340, 
// AU.AG..GU
170, 170, 50, 220, 410, 410, 290, 460, 290, 290, 170, 340, 410, 410, 290, 460, 
// AU.AU..GU
350, 350, 230, 400, 290, 290, 170, 340, 350, 350, 230, 400, 190, 190, 70, 240, 
// AU.CA..GU
290, 290, 370, 290, 290, 290, 370, 290, 170, 170, 250, 170, 410, 410, 490, 410, 
// AU.CC..GU
290, 290, 370, 290, 290, 290, 370, 290, 350, 350, 430, 350, 290, 290, 370, 290, 
// AU.CG..GU
170, 170, 250, 170, 410, 410, 490, 410, 290, 290, 370, 290, 410, 410, 490, 410, 
// AU.CU..GU
350, 350, 430, 350, 290, 290, 370, 290, 350, 350, 430, 350, 190, 190, 270, 190, 
// AU.GA..GU
170, 340, 290, 340, 170, 340, 290, 340, 50, 220, 170, 220, 290, 460, 410, 460, 
// AU.GC..GU
170, 340, 290, 340, 170, 340, 290, 340, 230, 400, 350, 400, 170, 340, 290, 340, 
// AU.GG..GU
50, 220, 170, 220, 290, 460, 410, 460, 170, 340, 290, 340, 290, 460, 410, 460, 
// AU.GU..GU
230, 400, 350, 400, 170, 340, 290, 340, 230, 400, 350, 400, 70, 240, 190, 240, 
// AU.UA..GU
360, 290, 360, 190, 360, 290, 360, 190, 240, 170, 240, 70, 480, 410, 480, 310, 
// AU.UC..GU
360, 290, 360, 190, 360, 290, 360, 190, 420, 350, 420, 250, 360, 290, 360, 190, 
// AU.UG..GU
240, 170, 240, 70, 480, 410, 480, 310, 360, 290, 360, 190, 480, 410, 480, 310, 
// AU.UU..GU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// AU.AA..UG
240, 240, 120, 290, 240, 240, 120, 290, 120, 120, 0, 170, 310, 310, 190, 360, 
// AU.AC..UG
240, 240, 120, 290, 240, 240, 120, 290, 240, 240, 120, 290, 240, 240, 120, 290, 
// AU.AG..UG
120, 120, 0, 170, 330, 330, 210, 380, 240, 240, 120, 290, 310, 310, 190, 360, 
// AU.AU..UG
260, 260, 140, 310, 240, 240, 120, 290, 240, 240, 120, 290, 140, 140, 20, 190, 
// AU.CA..UG
240, 240, 320, 240, 240, 240, 320, 240, 120, 120, 200, 120, 310, 310, 390, 310, 
// AU.CC..UG
240, 240, 320, 240, 240, 240, 320, 240, 240, 240, 320, 240, 240, 240, 320, 240, 
// AU.CG..UG
120, 120, 200, 120, 330, 330, 410, 330, 240, 240, 320, 240, 310, 310, 390, 310, 
// AU.CU..UG
260, 260, 340, 260, 240, 240, 320, 240, 240, 240, 320, 240, 140, 140, 220, 140, 
// AU.GA..UG
120, 290, 240, 290, 120, 290, 240, 290, 0, 170, 120, 170, 190, 360, 310, 360, 
// AU.GC..UG
120, 290, 240, 290, 120, 290, 240, 290, 120, 290, 240, 290, 120, 290, 240, 290, 
// AU.GG..UG
0, 170, 120, 170, 210, 380, 330, 380, 120, 290, 240, 290, 190, 360, 310, 360, 
// AU.GU..UG
140, 310, 260, 310, 120, 290, 240, 290, 120, 290, 240, 290, 20, 190, 140, 190, 
// AU.UA..UG
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 380, 310, 380, 210, 
// AU.UC..UG
310, 240, 310, 140, 310, 240, 310, 140, 310, 240, 310, 140, 310, 240, 310, 140, 
// AU.UG..UG
190, 120, 190, 20, 400, 330, 400, 230, 310, 240, 310, 140, 380, 310, 380, 210, 
// AU.UU..UG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// CG.AA..AU
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 360, 360, 240, 320, 
// CG.AC..AU
240, 240, 120, 200, 240, 240, 120, 200, 300, 300, 180, 260, 240, 240, 120, 200, 
// CG.AG..AU
120, 120, 0, 80, 360, 360, 240, 320, 240, 240, 120, 200, 360, 360, 240, 320, 
// CG.AU..AU
300, 300, 180, 260, 240, 240, 120, 200, 300, 300, 180, 260, 140, 140, 20, 100, 
// CG.CA..AU
240, 240, 290, 240, 240, 240, 290, 240, 120, 120, 170, 120, 360, 360, 410, 360, 
// CG.CC..AU
240, 240, 290, 240, 240, 240, 290, 240, 300, 300, 350, 300, 240, 240, 290, 240, 
// CG.CG..AU
120, 120, 170, 120, 360, 360, 410, 360, 240, 240, 290, 240, 360, 360, 410, 360, 
// CG.CU..AU
300, 300, 350, 300, 240, 240, 290, 240, 300, 300, 350, 300, 140, 140, 190, 140, 
// CG.GA..AU
120, 200, 240, 200, 120, 200, 240, 200, 0, 80, 120, 80, 240, 320, 360, 320, 
// CG.GC..AU
120, 200, 240, 200, 120, 200, 240, 200, 180, 260, 300, 260, 120, 200, 240, 200, 
// CG.GG..AU
0, 80, 120, 80, 240, 320, 360, 320, 120, 200, 240, 200, 240, 320, 360, 320, 
// CG.GU..AU
180, 260, 300, 260, 120, 200, 240, 200, 180, 260, 300, 260, 20, 100, 140, 100, 
// CG.UA..AU
250, 240, 250, 140, 250, 240, 250, 140, 130, 120, 130, 20, 370, 360, 370, 260, 
// CG.UC..AU
250, 240, 250, 140, 250, 240, 250, 140, 310, 300, 310, 200, 250, 240, 250, 140, 
// CG.UG..AU
130, 120, 130, 20, 370, 360, 370, 260, 250, 240, 250, 140, 370, 360, 370, 260, 
// CG.UU..AU
310, 300, 310, 200, 250, 240, 250, 140, 310, 300, 310, 200, 150, 140, 150, 40, 
// CG.AA..CG
190, 190, 70, 150, 190, 190, 70, 150, 70, 70, -50, 30, 260, 260, 140, 220, 
// CG.AC..CG
190, 190, 70, 150, 190, 190, 70, 150, 190, 190, 70, 150, 190, 190, 70, 150, 
// CG.AG..CG
70, 70, -50, 30, 280, 280, 160, 240, 190, 190, 70, 150, 260, 260, 140, 220, 
// CG.AU..CG
210, 210, 90, 170, 190, 190, 70, 150, 190, 190, 70, 150, 90, 90, -30, 50, 
// CG.CA..CG
190, 190, 240, 190, 190, 190, 240, 190, 70, 70, 120, 70, 260, 260, 310, 260, 
// CG.CC..CG
190, 190, 240, 190, 190, 190, 240, 190, 190, 190, 240, 190, 190, 190, 240, 190, 
// CG.CG..CG
70, 70, 120, 70, 280, 280, 330, 280, 190, 190, 240, 190, 260, 260, 310, 260, 
// CG.CU..CG
210, 210, 260, 210, 190, 190, 240, 190, 190, 190, 240, 190, 90, 90, 140, 90, 
// CG.GA..CG
70, 150, 190, 150, 70, 150, 190, 150, -50, 30, 70, 30, 140, 220, 260, 220, 
// CG.GC..CG
70, 150, 190, 150, 70, 150, 190, 150, 70, 150, 190, 150, 70, 150, 190, 150, 
// CG.GG..CG
-50, 30, 70, 30, 160, 240, 280, 240, 70, 150, 190, 150, 140, 220, 260, 220, 
// CG.GU..CG
90, 170, 210, 170, 70, 150, 190, 150, 70, 150, 190, 150, -30, 50, 90, 50, 
// CG.UA..CG
200, 190, 200, 90, 200, 190, 200, 90, 80, 70, 80, -30, 270, 260, 270, 160, 
// CG.UC..CG
200, 190, 200, 90, 200, 190, 200, 90, 200, 190, 200, 90, 200, 190, 200, 90, 
// CG.UG..CG
80, 70, 80, -30, 290, 280, 290, 180, 200, 190, 200, 90, 270, 260, 270, 160, 
// CG.UU..CG
220, 210, 220, 110, 200, 190, 200, 90, 200, 190, 200, 90, 100, 90, 100, -10, 
// CG.AA..GC
190, 190, 70, 150, 190, 190, 70, 150, 70, 70, -50, 30, 200, 200, 80, 160, 
// CG.AC..GC
190, 190, 70, 150, 190, 190, 70, 150, 150, 150, 30, 110, 190, 190, 70, 150, 
// CG.AG..GC
70, 70, -50, 30, 240, 240, 120, 200, 190, 190, 70, 150, 200, 200, 80, 160, 
// CG.AU..GC
150, 150, 30, 110, 190, 190, 70, 150, 150, 150, 30, 110, 90, 90, -30, 50, 
// CG.CA..GC
190, 190, 240, 190, 190, 190, 240, 190, 70, 70, 120, 70, 200, 200, 250, 200, 
// CG.CC..GC
190, 190, 240, 190, 190, 190, 240, 190, 150, 150, 200, 150, 190, 190, 240, 190, 
// CG.CG..GC
70, 70, 120, 70, 240, 240, 290, 240, 190, 190, 240, 190, 200, 200, 250, 200, 
// CG.CU..GC
150, 150, 200, 150, 190, 190, 240, 190, 150, 150, 200, 150, 90, 90, 140, 90, 
// CG.GA..GC
70, 150, 190, 150, 70, 150, 190, 150, -50, 30, 70, 30, 80, 160, 200, 160, 
// CG.GC..GC
70, 150, 190, 150, 70, 150, 190, 150, 30, 110, 150, 110, 70, 150, 190, 150, 
// CG.GG..GC
-50, 30, 70, 30, 120, 200, 240, 200, 70, 150, 190, 150, 80, 160, 200, 160, 
// CG.GU..GC
30, 110, 150, 110, 70, 150, 190, 150, 30, 110, 150, 110, -30, 50, 90, 50, 
// CG.UA..GC
200, 190, 200, 90, 200, 190, 200, 90, 80, 70, 80, -30, 210, 200, 210, 100, 
// CG.UC..GC
200, 190, 200, 90, 200, 190, 200, 90, 160, 150, 160, 50, 200, 190, 200, 90, 
// CG.UG..GC
80, 70, 80, -30, 250, 240, 250, 140, 200, 190, 200, 90, 210, 200, 210, 100, 
// CG.UU..GC
160, 150, 160, 50, 200, 190, 200, 90, 160, 150, 160, 50, 100, 90, 100, -10, 
// CG.AA..UA
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 310, 310, 190, 270, 
// CG.AC..UA
240, 240, 120, 200, 240, 240, 120, 200, 290, 290, 170, 250, 240, 240, 120, 200, 
// CG.AG..UA
120, 120, 0, 80, 320, 320, 200, 280, 240, 240, 120, 200, 310, 310, 190, 270, 
// CG.AU..UA
290, 290, 170, 250, 240, 240, 120, 200, 290, 290, 170, 250, 140, 140, 20, 100, 
// CG.CA..UA
240, 240, 290, 240, 240, 240, 290, 240, 120, 120, 170, 120, 310, 310, 360, 310, 
// CG.CC..UA
240, 240, 290, 240, 240, 240, 290, 240, 290, 290, 340, 290, 240, 240, 290, 240, 
// CG.CG..UA
120, 120, 170, 120, 320, 320, 370, 320, 240, 240, 290, 240, 310, 310, 360, 310, 
// CG.CU..UA
290, 290, 340, 290, 240, 240, 290, 240, 290, 290, 340, 290, 140, 140, 190, 140, 
// CG.GA..UA
120, 200, 240, 200, 120, 200, 240, 200, 0, 80, 120, 80, 190, 270, 310, 270, 
// CG.GC..UA
120, 200, 240, 200, 120, 200, 240, 200, 170, 250, 290, 250, 120, 200, 240, 200, 
// CG.GG..UA
0, 80, 120, 80, 200, 280, 320, 280, 120, 200, 240, 200, 190, 270, 310, 270, 
// CG.GU..UA
170, 250, 290, 250, 120, 200, 240, 200, 170, 250, 290, 250, 20, 100, 140, 100, 
// CG.UA..UA
250, 240, 250, 140, 250, 240, 250, 140, 130, 120, 130, 20, 320, 310, 320, 210, 
// CG.UC..UA
250, 240, 250, 140, 250, 240, 250, 140, 300, 290, 300, 190, 250, 240, 250, 140, 
// CG.UG..UA
130, 120, 130, 20, 330, 320, 330, 220, 250, 240, 250, 140, 320, 310, 320, 210, 
// CG.UU..UA
300, 290, 300, 190, 250, 240, 250, 140, 300, 290, 300, 190, 150, 140, 150, 40, 
// CG.AA..GU
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 360, 360, 240, 320, 
// CG.AC..GU
240, 240, 120, 200, 240, 240, 120, 200, 300, 300, 180, 260, 240, 240, 120, 200, 
// CG.AG..GU
120, 120, 0, 80, 360, 360, 240, 320, 240, 240, 120, 200, 360, 360, 240, 320, 
// CG.AU..GU
300, 300, 180, 260, 240, 240, 120, 200, 300, 300, 180, 260, 140, 140, 20, 100, 
// CG.CA..GU
240, 240, 290, 240, 240, 240, 290, 240, 120, 120, 170, 120, 360, 360, 410, 360, 
// CG.CC..GU
240, 240, 290, 240, 240, 240, 290, 240, 300, 300, 350, 300, 240, 240, 290, 240, 
// CG.CG..GU
120, 120, 170, 120, 360, 360, 410, 360, 240, 240, 290, 240, 360, 360, 410, 360, 
// CG.CU..GU
300, 300, 350, 300, 240, 240, 290, 240, 300, 300, 350, 300, 140, 140, 190, 140, 
// CG.GA..GU
120, 200, 240, 200, 120, 200, 240, 200, 0, 80, 120, 80, 240, 320, 360, 320, 
// CG.GC..GU
120, 200, 240, 200, 120, 200, 240, 200, 180, 260, 300, 260, 120, 200, 240, 200, 
// CG.GG..GU
0, 80, 120, 80, 240, 320, 360, 320, 120, 200, 240, 200, 240, 320, 360, 320, 
// CG.GU..GU
180, 260, 300, 260, 120, 200, 240, 200, 180, 260, 300, 260, 20, 100, 140, 100, 
// CG.UA..GU
250, 240, 250, 140, 250, 240, 250, 140, 130, 120, 130, 20, 370, 360, 370, 260, 
// CG.UC..GU
250, 240, 250, 140, 250, 240, 250, 140, 310, 300, 310, 200, 250, 240, 250, 140, 
// CG.UG..GU
130, 120, 130, 20, 370, 360, 370, 260, 250, 240, 250, 140, 370, 360, 370, 260, 
// CG.UU..GU
310, 300, 310, 200, 250, 240, 250, 140, 310, 300, 310, 200, 150, 140, 150, 40, 
// CG.AA..UG
190, 190, 70, 150, 190, 190, 70, 150, 70, 70, -50, 30, 260, 260, 140, 220, 
// CG.AC..UG
190, 190, 70, 150, 190, 190, 70, 150, 190, 190, 70, 150, 190, 190, 70, 150, 
// CG.AG..UG
70, 70, -50, 30, 280, 280, 160, 240, 190, 190, 70, 150, 260, 260, 140, 220, 
// CG.AU..UG
210, 210, 90, 170, 190, 190, 70, 150, 190, 190, 70, 150, 90, 90, -30, 50, 
// CG.CA..UG
190, 190, 240, 190, 190, 190, 240, 190, 70, 70, 120, 70, 260, 260, 310, 260, 
// CG.CC..UG
190, 190, 240, 190, 190, 190, 240, 190, 190, 190, 240, 190, 190, 190, 240, 190, 
// CG.CG..UG
70, 70, 120, 70, 280, 280, 330, 280, 190, 190, 240, 190, 260, 260, 310, 260, 
// CG.CU..UG
210, 210, 260, 210, 190, 190, 240, 190, 190, 190, 240, 190, 90, 90, 140, 90, 
// CG.GA..UG
70, 150, 190, 150, 70, 150, 190, 150, -50, 30, 70, 30, 140, 220, 260, 220, 
// CG.GC..UG
70, 150, 190, 150, 70, 150, 190, 150, 70, 150, 190, 150, 70, 150, 190, 150, 
// CG.GG..UG
-50, 30, 70, 30, 160, 240, 280, 240, 70, 150, 190, 150, 140, 220, 260, 220, 
// CG.GU..UG
90, 170, 210, 170, 70, 150, 190, 150, 70, 150, 190, 150, -30, 50, 90, 50, 
// CG.UA..UG
200, 190, 200, 90, 200, 190, 200, 90, 80, 70, 80, -30, 270, 260, 270, 160, 
// CG.UC..UG
200, 190, 200, 90, 200, 190, 200, 90, 200, 190, 200, 90, 200, 190, 200, 90, 
// CG.UG..UG
80, 70, 80, -30, 290, 280, 290, 180, 200, 190, 200, 90, 270, 260, 270, 160, 
// CG.UU..UG
220, 210, 220, 110, 200, 190, 200, 90, 200, 190, 200, 90, 100, 90, 100, -10, 
// GC.AA..AU
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 360, 360, 240, 380, 
// GC.AC..AU
240, 240, 120, 260, 240, 240, 120, 260, 300, 300, 180, 320, 240, 240, 120, 260, 
// GC.AG..AU
120, 120, 0, 140, 360, 360, 240, 380, 240, 240, 120, 260, 360, 360, 240, 380, 
// GC.AU..AU
300, 300, 180, 320, 240, 240, 120, 260, 300, 300, 180, 320, 140, 140, 20, 160, 
// GC.CA..AU
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 360, 360, 450, 360, 
// GC.CC..AU
240, 240, 330, 240, 240, 240, 330, 240, 300, 300, 390, 300, 240, 240, 330, 240, 
// GC.CG..AU
120, 120, 210, 120, 360, 360, 450, 360, 240, 240, 330, 240, 360, 360, 450, 360, 
// GC.CU..AU
300, 300, 390, 300, 240, 240, 330, 240, 300, 300, 390, 300, 140, 140, 230, 140, 
// GC.GA..AU
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 240, 360, 360, 360, 
// GC.GC..AU
120, 240, 240, 240, 120, 240, 240, 240, 180, 300, 300, 300, 120, 240, 240, 240, 
// GC.GG..AU
0, 120, 120, 120, 240, 360, 360, 360, 120, 240, 240, 240, 240, 360, 360, 360, 
// GC.GU..AU
180, 300, 300, 300, 120, 240, 240, 240, 180, 300, 300, 300, 20, 140, 140, 140, 
// GC.UA..AU
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 430, 360, 430, 260, 
// GC.UC..AU
310, 240, 310, 140, 310, 240, 310, 140, 370, 300, 370, 200, 310, 240, 310, 140, 
// GC.UG..AU
190, 120, 190, 20, 430, 360, 430, 260, 310, 240, 310, 140, 430, 360, 430, 260, 
// GC.UU..AU
370, 300, 370, 200, 310, 240, 310, 140, 370, 300, 370, 200, 210, 140, 210, 40, 
// GC.AA..CG
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 260, 260, 140, 280, 
// GC.AC..CG
190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 
// GC.AG..CG
70, 70, -50, 90, 280, 280, 160, 300, 190, 190, 70, 210, 260, 260, 140, 280, 
// GC.AU..CG
210, 210, 90, 230, 190, 190, 70, 210, 190, 190, 70, 210, 90, 90, -30, 110, 
// GC.CA..CG
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 260, 260, 350, 260, 
// GC.CC..CG
190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 
// GC.CG..CG
70, 70, 160, 70, 280, 280, 370, 280, 190, 190, 280, 190, 260, 260, 350, 260, 
// GC.CU..CG
210, 210, 300, 210, 190, 190, 280, 190, 190, 190, 280, 190, 90, 90, 180, 90, 
// GC.GA..CG
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 140, 260, 260, 260, 
// GC.GC..CG
70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 
// GC.GG..CG
-50, 70, 70, 70, 160, 280, 280, 280, 70, 190, 190, 190, 140, 260, 260, 260, 
// GC.GU..CG
90, 210, 210, 210, 70, 190, 190, 190, 70, 190, 190, 190, -30, 90, 90, 90, 
// GC.UA..CG
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 330, 260, 330, 160, 
// GC.UC..CG
260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 
// GC.UG..CG
140, 70, 140, -30, 350, 280, 350, 180, 260, 190, 260, 90, 330, 260, 330, 160, 
// GC.UU..CG
280, 210, 280, 110, 260, 190, 260, 90, 260, 190, 260, 90, 160, 90, 160, -10, 
// GC.AA..GC
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 200, 200, 80, 220, 
// GC.AC..GC
190, 190, 70, 210, 190, 190, 70, 210, 150, 150, 30, 170, 190, 190, 70, 210, 
// GC.AG..GC
70, 70, -50, 90, 240, 240, 120, 260, 190, 190, 70, 210, 200, 200, 80, 220, 
// GC.AU..GC
150, 150, 30, 170, 190, 190, 70, 210, 150, 150, 30, 170, 90, 90, -30, 110, 
// GC.CA..GC
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 200, 200, 290, 200, 
// GC.CC..GC
190, 190, 280, 190, 190, 190, 280, 190, 150, 150, 240, 150, 190, 190, 280, 190, 
// GC.CG..GC
70, 70, 160, 70, 240, 240, 330, 240, 190, 190, 280, 190, 200, 200, 290, 200, 
// GC.CU..GC
150, 150, 240, 150, 190, 190, 280, 190, 150, 150, 240, 150, 90, 90, 180, 90, 
// GC.GA..GC
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 80, 200, 200, 200, 
// GC.GC..GC
70, 190, 190, 190, 70, 190, 190, 190, 30, 150, 150, 150, 70, 190, 190, 190, 
// GC.GG..GC
-50, 70, 70, 70, 120, 240, 240, 240, 70, 190, 190, 190, 80, 200, 200, 200, 
// GC.GU..GC
30, 150, 150, 150, 70, 190, 190, 190, 30, 150, 150, 150, -30, 90, 90, 90, 
// GC.UA..GC
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 270, 200, 270, 100, 
// GC.UC..GC
260, 190, 260, 90, 260, 190, 260, 90, 220, 150, 220, 50, 260, 190, 260, 90, 
// GC.UG..GC
140, 70, 140, -30, 310, 240, 310, 140, 260, 190, 260, 90, 270, 200, 270, 100, 
// GC.UU..GC
220, 150, 220, 50, 260, 190, 260, 90, 220, 150, 220, 50, 160, 90, 160, -10, 
// GC.AA..UA
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GC.AC..UA
240, 240, 120, 260, 240, 240, 120, 260, 290, 290, 170, 310, 240, 240, 120, 260, 
// GC.AG..UA
120, 120, 0, 140, 320, 320, 200, 340, 240, 240, 120, 260, 310, 310, 190, 330, 
// GC.AU..UA
290, 290, 170, 310, 240, 240, 120, 260, 290, 290, 170, 310, 140, 140, 20, 160, 
// GC.CA..UA
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 310, 310, 400, 310, 
// GC.CC..UA
240, 240, 330, 240, 240, 240, 330, 240, 290, 290, 380, 290, 240, 240, 330, 240, 
// GC.CG..UA
120, 120, 210, 120, 320, 320, 410, 320, 240, 240, 330, 240, 310, 310, 400, 310, 
// GC.CU..UA
290, 290, 380, 290, 240, 240, 330, 240, 290, 290, 380, 290, 140, 140, 230, 140, 
// GC.GA..UA
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 190, 310, 310, 310, 
// GC.GC..UA
120, 240, 240, 240, 120, 240, 240, 240, 170, 290, 290, 290, 120, 240, 240, 240, 
// GC.GG..UA
0, 120, 120, 120, 200, 320, 320, 320, 120, 240, 240, 240, 190, 310, 310, 310, 
// GC.GU..UA
170, 290, 290, 290, 120, 240, 240, 240, 170, 290, 290, 290, 20, 140, 140, 140, 
// GC.UA..UA
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 380, 310, 380, 210, 
// GC.UC..UA
310, 240, 310, 140, 310, 240, 310, 140, 360, 290, 360, 190, 310, 240, 310, 140, 
// GC.UG..UA
190, 120, 190, 20, 390, 320, 390, 220, 310, 240, 310, 140, 380, 310, 380, 210, 
// GC.UU..UA
360, 290, 360, 190, 310, 240, 310, 140, 360, 290, 360, 190, 210, 140, 210, 40, 
// GC.AA..GU
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 360, 360, 240, 380, 
// GC.AC..GU
240, 240, 120, 260, 240, 240, 120, 260, 300, 300, 180, 320, 240, 240, 120, 260, 
// GC.AG..GU
120, 120, 0, 140, 360, 360, 240, 380, 240, 240, 120, 260, 360, 360, 240, 380, 
// GC.AU..GU
300, 300, 180, 320, 240, 240, 120, 260, 300, 300, 180, 320, 140, 140, 20, 160, 
// GC.CA..GU
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 360, 360, 450, 360, 
// GC.CC..GU
240, 240, 330, 240, 240, 240, 330, 240, 300, 300, 390, 300, 240, 240, 330, 240, 
// GC.CG..GU
120, 120, 210, 120, 360, 360, 450, 360, 240, 240, 330, 240, 360, 360, 450, 360, 
// GC.CU..GU
300, 300, 390, 300, 240, 240, 330, 240, 300, 300, 390, 300, 140, 140, 230, 140, 
// GC.GA..GU
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 240, 360, 360, 360, 
// GC.GC..GU
120, 240, 240, 240, 120, 240, 240, 240, 180, 300, 300, 300, 120, 240, 240, 240, 
// GC.GG..GU
0, 120, 120, 120, 240, 360, 360, 360, 120, 240, 240, 240, 240, 360, 360, 360, 
// GC.GU..GU
180, 300, 300, 300, 120, 240, 240, 240, 180, 300, 300, 300, 20, 140, 140, 140, 
// GC.UA..GU
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 430, 360, 430, 260, 
// GC.UC..GU
310, 240, 310, 140, 310, 240, 310, 140, 370, 300, 370, 200, 310, 240, 310, 140, 
// GC.UG..GU
190, 120, 190, 20, 430, 360, 430, 260, 310, 240, 310, 140, 430, 360, 430, 260, 
// GC.UU..GU
370, 300, 370, 200, 310, 240, 310, 140, 370, 300, 370, 200, 210, 140, 210, 40, 
// GC.AA..UG
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 260, 260, 140, 280, 
// GC.AC..UG
190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 
// GC.AG..UG
70, 70, -50, 90, 280, 280, 160, 300, 190, 190, 70, 210, 260, 260, 140, 280, 
// GC.AU..UG
210, 210, 90, 230, 190, 190, 70, 210, 190, 190, 70, 210, 90, 90, -30, 110, 
// GC.CA..UG
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 260, 260, 350, 260, 
// GC.CC..UG
190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 
// GC.CG..UG
70, 70, 160, 70, 280, 280, 370, 280, 190, 190, 280, 190, 260, 260, 350, 260, 
// GC.CU..UG
210, 210, 300, 210, 190, 190, 280, 190, 190, 190, 280, 190, 90, 90, 180, 90, 
// GC.GA..UG
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 140, 260, 260, 260, 
// GC.GC..UG
70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 
// GC.GG..UG
-50, 70, 70, 70, 160, 280, 280, 280, 70, 190, 190, 190, 140, 260, 260, 260, 
// GC.GU..UG
90, 210, 210, 210, 70, 190, 190, 190, 70, 190, 190, 190, -30, 90, 90, 90, 
// GC.UA..UG
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 330, 260, 330, 160, 
// GC.UC..UG
260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 
// GC.UG..UG
140, 70, 140, -30, 350, 280, 350, 180, 260, 190, 260, 90, 330, 260, 330, 160, 
// GC.UU..UG
280, 210, 280, 110, 260, 190, 260, 90, 260, 190, 260, 90, 160, 90, 160, -10, 
// UA.AA..AU
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 410, 410, 290, 470, 
// UA.AC..AU
290, 290, 170, 350, 290, 290, 170, 350, 350, 350, 230, 410, 290, 290, 170, 350, 
// UA.AG..AU
170, 170, 50, 230, 410, 410, 290, 470, 290, 290, 170, 350, 410, 410, 290, 470, 
// UA.AU..AU
350, 350, 230, 410, 290, 290, 170, 350, 350, 350, 230, 410, 190, 190, 70, 250, 
// UA.CA..AU
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 410, 410, 530, 410, 
// UA.CC..AU
290, 290, 410, 290, 290, 290, 410, 290, 350, 350, 470, 350, 290, 290, 410, 290, 
// UA.CG..AU
170, 170, 290, 170, 410, 410, 530, 410, 290, 290, 410, 290, 410, 410, 530, 410, 
// UA.CU..AU
350, 350, 470, 350, 290, 290, 410, 290, 350, 350, 470, 350, 190, 190, 310, 190, 
// UA.GA..AU
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 290, 470, 410, 470, 
// UA.GC..AU
170, 350, 290, 350, 170, 350, 290, 350, 230, 410, 350, 410, 170, 350, 290, 350, 
// UA.GG..AU
50, 230, 170, 230, 290, 470, 410, 470, 170, 350, 290, 350, 290, 470, 410, 470, 
// UA.GU..AU
230, 410, 350, 410, 170, 350, 290, 350, 230, 410, 350, 410, 70, 250, 190, 250, 
// UA.UA..AU
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 530, 410, 530, 310, 
// UA.UC..AU
410, 290, 410, 190, 410, 290, 410, 190, 470, 350, 470, 250, 410, 290, 410, 190, 
// UA.UG..AU
290, 170, 290, 70, 530, 410, 530, 310, 410, 290, 410, 190, 530, 410, 530, 310, 
// UA.UU..AU
470, 350, 470, 250, 410, 290, 410, 190, 470, 350, 470, 250, 310, 190, 310, 90, 
// UA.AA..CG
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 310, 310, 190, 370, 
// UA.AC..CG
240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 
// UA.AG..CG
120, 120, 0, 180, 330, 330, 210, 390, 240, 240, 120, 300, 310, 310, 190, 370, 
// UA.AU..CG
260, 260, 140, 320, 240, 240, 120, 300, 240, 240, 120, 300, 140, 140, 20, 200, 
// UA.CA..CG
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 310, 310, 430, 310, 
// UA.CC..CG
240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 
// UA.CG..CG
120, 120, 240, 120, 330, 330, 450, 330, 240, 240, 360, 240, 310, 310, 430, 310, 
// UA.CU..CG
260, 260, 380, 260, 240, 240, 360, 240, 240, 240, 360, 240, 140, 140, 260, 140, 
// UA.GA..CG
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 190, 370, 310, 370, 
// UA.GC..CG
120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 
// UA.GG..CG
0, 180, 120, 180, 210, 390, 330, 390, 120, 300, 240, 300, 190, 370, 310, 370, 
// UA.GU..CG
140, 320, 260, 320, 120, 300, 240, 300, 120, 300, 240, 300, 20, 200, 140, 200, 
// UA.UA..CG
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 430, 310, 430, 210, 
// UA.UC..CG
360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 
// UA.UG..CG
240, 120, 240, 20, 450, 330, 450, 230, 360, 240, 360, 140, 430, 310, 430, 210, 
// UA.UU..CG
380, 260, 380, 160, 360, 240, 360, 140, 360, 240, 360, 140, 260, 140, 260, 40, 
// UA.AA..GC
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 250, 250, 130, 310, 
// UA.AC..GC
240, 240, 120, 300, 240, 240, 120, 300, 200, 200, 80, 260, 240, 240, 120, 300, 
// UA.AG..GC
120, 120, 0, 180, 290, 290, 170, 350, 240, 240, 120, 300, 250, 250, 130, 310, 
// UA.AU..GC
200, 200, 80, 260, 240, 240, 120, 300, 200, 200, 80, 260, 140, 140, 20, 200, 
// UA.CA..GC
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 250, 250, 370, 250, 
// UA.CC..GC
240, 240, 360, 240, 240, 240, 360, 240, 200, 200, 320, 200, 240, 240, 360, 240, 
// UA.CG..GC
120, 120, 240, 120, 290, 290, 410, 290, 240, 240, 360, 240, 250, 250, 370, 250, 
// UA.CU..GC
200, 200, 320, 200, 240, 240, 360, 240, 200, 200, 320, 200, 140, 140, 260, 140, 
// UA.GA..GC
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 130, 310, 250, 310, 
// UA.GC..GC
120, 300, 240, 300, 120, 300, 240, 300, 80, 260, 200, 260, 120, 300, 240, 300, 
// UA.GG..GC
0, 180, 120, 180, 170, 350, 290, 350, 120, 300, 240, 300, 130, 310, 250, 310, 
// UA.GU..GC
80, 260, 200, 260, 120, 300, 240, 300, 80, 260, 200, 260, 20, 200, 140, 200, 
// UA.UA..GC
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 370, 250, 370, 150, 
// UA.UC..GC
360, 240, 360, 140, 360, 240, 360, 140, 320, 200, 320, 100, 360, 240, 360, 140, 
// UA.UG..GC
240, 120, 240, 20, 410, 290, 410, 190, 360, 240, 360, 140, 370, 250, 370, 150, 
// UA.UU..GC
320, 200, 320, 100, 360, 240, 360, 140, 320, 200, 320, 100, 260, 140, 260, 40, 
// UA.AA..UA
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UA.AC..UA
290, 290, 170, 350, 290, 290, 170, 350, 340, 340, 220, 400, 290, 290, 170, 350, 
// UA.AG..UA
170, 170, 50, 230, 370, 370, 250, 430, 290, 290, 170, 350, 360, 360, 240, 420, 
// UA.AU..UA
340, 340, 220, 400, 290, 290, 170, 350, 340, 340, 220, 400, 190, 190, 70, 250, 
// UA.CA..UA
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 360, 360, 480, 360, 
// UA.CC..UA
290, 290, 410, 290, 290, 290, 410, 290, 340, 340, 460, 340, 290, 290, 410, 290, 
// UA.CG..UA
170, 170, 290, 170, 370, 370, 490, 370, 290, 290, 410, 290, 360, 360, 480, 360, 
// UA.CU..UA
340, 340, 460, 340, 290, 290, 410, 290, 340, 340, 460, 340, 190, 190, 310, 190, 
// UA.GA..UA
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 240, 420, 360, 420, 
// UA.GC..UA
170, 350, 290, 350, 170, 350, 290, 350, 220, 400, 340, 400, 170, 350, 290, 350, 
// UA.GG..UA
50, 230, 170, 230, 250, 430, 370, 430, 170, 350, 290, 350, 240, 420, 360, 420, 
// UA.GU..UA
220, 400, 340, 400, 170, 350, 290, 350, 220, 400, 340, 400, 70, 250, 190, 250, 
// UA.UA..UA
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 480, 360, 480, 260, 
// UA.UC..UA
410, 290, 410, 190, 410, 290, 410, 190, 460, 340, 460, 240, 410, 290, 410, 190, 
// UA.UG..UA
290, 170, 290, 70, 490, 370, 490, 270, 410, 290, 410, 190, 480, 360, 480, 260, 
// UA.UU..UA
460, 340, 460, 240, 410, 290, 410, 190, 460, 340, 460, 240, 310, 190, 310, 90, 
// UA.AA..GU
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 410, 410, 290, 470, 
// UA.AC..GU
290, 290, 170, 350, 290, 290, 170, 350, 350, 350, 230, 410, 290, 290, 170, 350, 
// UA.AG..GU
170, 170, 50, 230, 410, 410, 290, 470, 290, 290, 170, 350, 410, 410, 290, 470, 
// UA.AU..GU
350, 350, 230, 410, 290, 290, 170, 350, 350, 350, 230, 410, 190, 190, 70, 250, 
// UA.CA..GU
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 410, 410, 530, 410, 
// UA.CC..GU
290, 290, 410, 290, 290, 290, 410, 290, 350, 350, 470, 350, 290, 290, 410, 290, 
// UA.CG..GU
170, 170, 290, 170, 410, 410, 530, 410, 290, 290, 410, 290, 410, 410, 530, 410, 
// UA.CU..GU
350, 350, 470, 350, 290, 290, 410, 290, 350, 350, 470, 350, 190, 190, 310, 190, 
// UA.GA..GU
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 290, 470, 410, 470, 
// UA.GC..GU
170, 350, 290, 350, 170, 350, 290, 350, 230, 410, 350, 410, 170, 350, 290, 350, 
// UA.GG..GU
50, 230, 170, 230, 290, 470, 410, 470, 170, 350, 290, 350, 290, 470, 410, 470, 
// UA.GU..GU
230, 410, 350, 410, 170, 350, 290, 350, 230, 410, 350, 410, 70, 250, 190, 250, 
// UA.UA..GU
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 530, 410, 530, 310, 
// UA.UC..GU
410, 290, 410, 190, 410, 290, 410, 190, 470, 350, 470, 250, 410, 290, 410, 190, 
// UA.UG..GU
290, 170, 290, 70, 530, 410, 530, 310, 410, 290, 410, 190, 530, 410, 530, 310, 
// UA.UU..GU
470, 350, 470, 250, 410, 290, 410, 190, 470, 350, 470, 250, 310, 190, 310, 90, 
// UA.AA..UG
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 310, 310, 190, 370, 
// UA.AC..UG
240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 
// UA.AG..UG
120, 120, 0, 180, 330, 330, 210, 390, 240, 240, 120, 300, 310, 310, 190, 370, 
// UA.AU..UG
260, 260, 140, 320, 240, 240, 120, 300, 240, 240, 120, 300, 140, 140, 20, 200, 
// UA.CA..UG
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 310, 310, 430, 310, 
// UA.CC..UG
240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 
// UA.CG..UG
120, 120, 240, 120, 330, 330, 450, 330, 240, 240, 360, 240, 310, 310, 430, 310, 
// UA.CU..UG
260, 260, 380, 260, 240, 240, 360, 240, 240, 240, 360, 240, 140, 140, 260, 140, 
// UA.GA..UG
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 190, 370, 310, 370, 
// UA.GC..UG
120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 
// UA.GG..UG
0, 180, 120, 180, 210, 390, 330, 390, 120, 300, 240, 300, 190, 370, 310, 370, 
// UA.GU..UG
140, 320, 260, 320, 120, 300, 240, 300, 120, 300, 240, 300, 20, 200, 140, 200, 
// UA.UA..UG
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 430, 310, 430, 210, 
// UA.UC..UG
360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 
// UA.UG..UG
240, 120, 240, 20, 450, 330, 450, 230, 360, 240, 360, 140, 430, 310, 430, 210, 
// UA.UU..UG
380, 260, 380, 160, 360, 240, 360, 140, 360, 240, 360, 140, 260, 140, 260, 40, 
// GU.AA..AU
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 360, 360, 240, 380, 
// GU.AC..AU
240, 240, 120, 260, 240, 240, 120, 260, 300, 300, 180, 320, 240, 240, 120, 260, 
// GU.AG..AU
120, 120, 0, 140, 360, 360, 240, 380, 240, 240, 120, 260, 360, 360, 240, 380, 
// GU.AU..AU
300, 300, 180, 320, 240, 240, 120, 260, 300, 300, 180, 320, 140, 140, 20, 160, 
// GU.CA..AU
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 360, 360, 450, 360, 
// GU.CC..AU
240, 240, 330, 240, 240, 240, 330, 240, 300, 300, 390, 300, 240, 240, 330, 240, 
// GU.CG..AU
120, 120, 210, 120, 360, 360, 450, 360, 240, 240, 330, 240, 360, 360, 450, 360, 
// GU.CU..AU
300, 300, 390, 300, 240, 240, 330, 240, 300, 300, 390, 300, 140, 140, 230, 140, 
// GU.GA..AU
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 240, 360, 360, 360, 
// GU.GC..AU
120, 240, 240, 240, 120, 240, 240, 240, 180, 300, 300, 300, 120, 240, 240, 240, 
// GU.GG..AU
0, 120, 120, 120, 240, 360, 360, 360, 120, 240, 240, 240, 240, 360, 360, 360, 
// GU.GU..AU
180, 300, 300, 300, 120, 240, 240, 240, 180, 300, 300, 300, 20, 140, 140, 140, 
// GU.UA..AU
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 430, 360, 430, 260, 
// GU.UC..AU
310, 240, 310, 140, 310, 240, 310, 140, 370, 300, 370, 200, 310, 240, 310, 140, 
// GU.UG..AU
190, 120, 190, 20, 430, 360, 430, 260, 310, 240, 310, 140, 430, 360, 430, 260, 
// GU.UU..AU
370, 300, 370, 200, 310, 240, 310, 140, 370, 300, 370, 200, 210, 140, 210, 40, 
// GU.AA..CG
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 260, 260, 140, 280, 
// GU.AC..CG
190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 
// GU.AG..CG
70, 70, -50, 90, 280, 280, 160, 300, 190, 190, 70, 210, 260, 260, 140, 280, 
// GU.AU..CG
210, 210, 90, 230, 190, 190, 70, 210, 190, 190, 70, 210, 90, 90, -30, 110, 
// GU.CA..CG
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 260, 260, 350, 260, 
// GU.CC..CG
190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 
// GU.CG..CG
70, 70, 160, 70, 280, 280, 370, 280, 190, 190, 280, 190, 260, 260, 350, 260, 
// GU.CU..CG
210, 210, 300, 210, 190, 190, 280, 190, 190, 190, 280, 190, 90, 90, 180, 90, 
// GU.GA..CG
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 140, 260, 260, 260, 
// GU.GC..CG
70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 
// GU.GG..CG
-50, 70, 70, 70, 160, 280, 280, 280, 70, 190, 190, 190, 140, 260, 260, 260, 
// GU.GU..CG
90, 210, 210, 210, 70, 190, 190, 190, 70, 190, 190, 190, -30, 90, 90, 90, 
// GU.UA..CG
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 330, 260, 330, 160, 
// GU.UC..CG
260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 
// GU.UG..CG
140, 70, 140, -30, 350, 280, 350, 180, 260, 190, 260, 90, 330, 260, 330, 160, 
// GU.UU..CG
280, 210, 280, 110, 260, 190, 260, 90, 260, 190, 260, 90, 160, 90, 160, -10, 
// GU.AA..GC
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 200, 200, 80, 220, 
// GU.AC..GC
190, 190, 70, 210, 190, 190, 70, 210, 150, 150, 30, 170, 190, 190, 70, 210, 
// GU.AG..GC
70, 70, -50, 90, 240, 240, 120, 260, 190, 190, 70, 210, 200, 200, 80, 220, 
// GU.AU..GC
150, 150, 30, 170, 190, 190, 70, 210, 150, 150, 30, 170, 90, 90, -30, 110, 
// GU.CA..GC
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 200, 200, 290, 200, 
// GU.CC..GC
190, 190, 280, 190, 190, 190, 280, 190, 150, 150, 240, 150, 190, 190, 280, 190, 
// GU.CG..GC
70, 70, 160, 70, 240, 240, 330, 240, 190, 190, 280, 190, 200, 200, 290, 200, 
// GU.CU..GC
150, 150, 240, 150, 190, 190, 280, 190, 150, 150, 240, 150, 90, 90, 180, 90, 
// GU.GA..GC
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 80, 200, 200, 200, 
// GU.GC..GC
70, 190, 190, 190, 70, 190, 190, 190, 30, 150, 150, 150, 70, 190, 190, 190, 
// GU.GG..GC
-50, 70, 70, 70, 120, 240, 240, 240, 70, 190, 190, 190, 80, 200, 200, 200, 
// GU.GU..GC
30, 150, 150, 150, 70, 190, 190, 190, 30, 150, 150, 150, -30, 90, 90, 90, 
// GU.UA..GC
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 270, 200, 270, 100, 
// GU.UC..GC
260, 190, 260, 90, 260, 190, 260, 90, 220, 150, 220, 50, 260, 190, 260, 90, 
// GU.UG..GC
140, 70, 140, -30, 310, 240, 310, 140, 260, 190, 260, 90, 270, 200, 270, 100, 
// GU.UU..GC
220, 150, 220, 50, 260, 190, 260, 90, 220, 150, 220, 50, 160, 90, 160, -10, 
// GU.AA..UA
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GU.AC..UA
240, 240, 120, 260, 240, 240, 120, 260, 290, 290, 170, 310, 240, 240, 120, 260, 
// GU.AG..UA
120, 120, 0, 140, 320, 320, 200, 340, 240, 240, 120, 260, 310, 310, 190, 330, 
// GU.AU..UA
290, 290, 170, 310, 240, 240, 120, 260, 290, 290, 170, 310, 140, 140, 20, 160, 
// GU.CA..UA
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 310, 310, 400, 310, 
// GU.CC..UA
240, 240, 330, 240, 240, 240, 330, 240, 290, 290, 380, 290, 240, 240, 330, 240, 
// GU.CG..UA
120, 120, 210, 120, 320, 320, 410, 320, 240, 240, 330, 240, 310, 310, 400, 310, 
// GU.CU..UA
290, 290, 380, 290, 240, 240, 330, 240, 290, 290, 380, 290, 140, 140, 230, 140, 
// GU.GA..UA
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 190, 310, 310, 310, 
// GU.GC..UA
120, 240, 240, 240, 120, 240, 240, 240, 170, 290, 290, 290, 120, 240, 240, 240, 
// GU.GG..UA
0, 120, 120, 120, 200, 320, 320, 320, 120, 240, 240, 240, 190, 310, 310, 310, 
// GU.GU..UA
170, 290, 290, 290, 120, 240, 240, 240, 170, 290, 290, 290, 20, 140, 140, 140, 
// GU.UA..UA
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 380, 310, 380, 210, 
// GU.UC..UA
310, 240, 310, 140, 310, 240, 310, 140, 360, 290, 360, 190, 310, 240, 310, 140, 
// GU.UG..UA
190, 120, 190, 20, 390, 320, 390, 220, 310, 240, 310, 140, 380, 310, 380, 210, 
// GU.UU..UA
360, 290, 360, 190, 310, 240, 310, 140, 360, 290, 360, 190, 210, 140, 210, 40, 
// GU.AA..GU
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 360, 360, 240, 380, 
// GU.AC..GU
240, 240, 120, 260, 240, 240, 120, 260, 300, 300, 180, 320, 240, 240, 120, 260, 
// GU.AG..GU
120, 120, 0, 140, 360, 360, 240, 380, 240, 240, 120, 260, 360, 360, 240, 380, 
// GU.AU..GU
300, 300, 180, 320, 240, 240, 120, 260, 300, 300, 180, 320, 140, 140, 20, 160, 
// GU.CA..GU
240, 240, 330, 240, 240, 240, 330, 240, 120, 120, 210, 120, 360, 360, 450, 360, 
// GU.CC..GU
240, 240, 330, 240, 240, 240, 330, 240, 300, 300, 390, 300, 240, 240, 330, 240, 
// GU.CG..GU
120, 120, 210, 120, 360, 360, 450, 360, 240, 240, 330, 240, 360, 360, 450, 360, 
// GU.CU..GU
300, 300, 390, 300, 240, 240, 330, 240, 300, 300, 390, 300, 140, 140, 230, 140, 
// GU.GA..GU
120, 240, 240, 240, 120, 240, 240, 240, 0, 120, 120, 120, 240, 360, 360, 360, 
// GU.GC..GU
120, 240, 240, 240, 120, 240, 240, 240, 180, 300, 300, 300, 120, 240, 240, 240, 
// GU.GG..GU
0, 120, 120, 120, 240, 360, 360, 360, 120, 240, 240, 240, 240, 360, 360, 360, 
// GU.GU..GU
180, 300, 300, 300, 120, 240, 240, 240, 180, 300, 300, 300, 20, 140, 140, 140, 
// GU.UA..GU
310, 240, 310, 140, 310, 240, 310, 140, 190, 120, 190, 20, 430, 360, 430, 260, 
// GU.UC..GU
310, 240, 310, 140, 310, 240, 310, 140, 370, 300, 370, 200, 310, 240, 310, 140, 
// GU.UG..GU
190, 120, 190, 20, 430, 360, 430, 260, 310, 240, 310, 140, 430, 360, 430, 260, 
// GU.UU..GU
370, 300, 370, 200, 310, 240, 310, 140, 370, 300, 370, 200, 210, 140, 210, 40, 
// GU.AA..UG
190, 190, 70, 210, 190, 190, 70, 210, 70, 70, -50, 90, 260, 260, 140, 280, 
// GU.AC..UG
190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 190, 190, 70, 210, 
// GU.AG..UG
70, 70, -50, 90, 280, 280, 160, 300, 190, 190, 70, 210, 260, 260, 140, 280, 
// GU.AU..UG
210, 210, 90, 230, 190, 190, 70, 210, 190, 190, 70, 210, 90, 90, -30, 110, 
// GU.CA..UG
190, 190, 280, 190, 190, 190, 280, 190, 70, 70, 160, 70, 260, 260, 350, 260, 
// GU.CC..UG
190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 190, 190, 280, 190, 
// GU.CG..UG
70, 70, 160, 70, 280, 280, 370, 280, 190, 190, 280, 190, 260, 260, 350, 260, 
// GU.CU..UG
210, 210, 300, 210, 190, 190, 280, 190, 190, 190, 280, 190, 90, 90, 180, 90, 
// GU.GA..UG
70, 190, 190, 190, 70, 190, 190, 190, -50, 70, 70, 70, 140, 260, 260, 260, 
// GU.GC..UG
70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 70, 190, 190, 190, 
// GU.GG..UG
-50, 70, 70, 70, 160, 280, 280, 280, 70, 190, 190, 190, 140, 260, 260, 260, 
// GU.GU..UG
90, 210, 210, 210, 70, 190, 190, 190, 70, 190, 190, 190, -30, 90, 90, 90, 
// GU.UA..UG
260, 190, 260, 90, 260, 190, 260, 90, 140, 70, 140, -30, 330, 260, 330, 160, 
// GU.UC..UG
260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 260, 190, 260, 90, 
// GU.UG..UG
140, 70, 140, -30, 350, 280, 350, 180, 260, 190, 260, 90, 330, 260, 330, 160, 
// GU.UU..UG
280, 210, 280, 110, 260, 190, 260, 90, 260, 190, 260, 90, 160, 90, 160, -10, 
// UG.AA..AU
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 410, 410, 290, 470, 
// UG.AC..AU
290, 290, 170, 350, 290, 290, 170, 350, 350, 350, 230, 410, 290, 290, 170, 350, 
// UG.AG..AU
170, 170, 50, 230, 410, 410, 290, 470, 290, 290, 170, 350, 410, 410, 290, 470, 
// UG.AU..AU
350, 350, 230, 410, 290, 290, 170, 350, 350, 350, 230, 410, 190, 190, 70, 250, 
// UG.CA..AU
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 410, 410, 530, 410, 
// UG.CC..AU
290, 290, 410, 290, 290, 290, 410, 290, 350, 350, 470, 350, 290, 290, 410, 290, 
// UG.CG..AU
170, 170, 290, 170, 410, 410, 530, 410, 290, 290, 410, 290, 410, 410, 530, 410, 
// UG.CU..AU
350, 350, 470, 350, 290, 290, 410, 290, 350, 350, 470, 350, 190, 190, 310, 190, 
// UG.GA..AU
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 290, 470, 410, 470, 
// UG.GC..AU
170, 350, 290, 350, 170, 350, 290, 350, 230, 410, 350, 410, 170, 350, 290, 350, 
// UG.GG..AU
50, 230, 170, 230, 290, 470, 410, 470, 170, 350, 290, 350, 290, 470, 410, 470, 
// UG.GU..AU
230, 410, 350, 410, 170, 350, 290, 350, 230, 410, 350, 410, 70, 250, 190, 250, 
// UG.UA..AU
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 530, 410, 530, 310, 
// UG.UC..AU
410, 290, 410, 190, 410, 290, 410, 190, 470, 350, 470, 250, 410, 290, 410, 190, 
// UG.UG..AU
290, 170, 290, 70, 530, 410, 530, 310, 410, 290, 410, 190, 530, 410, 530, 310, 
// UG.UU..AU
470, 350, 470, 250, 410, 290, 410, 190, 470, 350, 470, 250, 310, 190, 310, 90, 
// UG.AA..CG
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 310, 310, 190, 370, 
// UG.AC..CG
240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 
// UG.AG..CG
120, 120, 0, 180, 330, 330, 210, 390, 240, 240, 120, 300, 310, 310, 190, 370, 
// UG.AU..CG
260, 260, 140, 320, 240, 240, 120, 300, 240, 240, 120, 300, 140, 140, 20, 200, 
// UG.CA..CG
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 310, 310, 430, 310, 
// UG.CC..CG
240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 
// UG.CG..CG
120, 120, 240, 120, 330, 330, 450, 330, 240, 240, 360, 240, 310, 310, 430, 310, 
// UG.CU..CG
260, 260, 380, 260, 240, 240, 360, 240, 240, 240, 360, 240, 140, 140, 260, 140, 
// UG.GA..CG
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 190, 370, 310, 370, 
// UG.GC..CG
120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 
// UG.GG..CG
0, 180, 120, 180, 210, 390, 330, 390, 120, 300, 240, 300, 190, 370, 310, 370, 
// UG.GU..CG
140, 320, 260, 320, 120, 300, 240, 300, 120, 300, 240, 300, 20, 200, 140, 200, 
// UG.UA..CG
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 430, 310, 430, 210, 
// UG.UC..CG
360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 
// UG.UG..CG
240, 120, 240, 20, 450, 330, 450, 230, 360, 240, 360, 140, 430, 310, 430, 210, 
// UG.UU..CG
380, 260, 380, 160, 360, 240, 360, 140, 360, 240, 360, 140, 260, 140, 260, 40, 
// UG.AA..GC
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 250, 250, 130, 310, 
// UG.AC..GC
240, 240, 120, 300, 240, 240, 120, 300, 200, 200, 80, 260, 240, 240, 120, 300, 
// UG.AG..GC
120, 120, 0, 180, 290, 290, 170, 350, 240, 240, 120, 300, 250, 250, 130, 310, 
// UG.AU..GC
200, 200, 80, 260, 240, 240, 120, 300, 200, 200, 80, 260, 140, 140, 20, 200, 
// UG.CA..GC
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 250, 250, 370, 250, 
// UG.CC..GC
240, 240, 360, 240, 240, 240, 360, 240, 200, 200, 320, 200, 240, 240, 360, 240, 
// UG.CG..GC
120, 120, 240, 120, 290, 290, 410, 290, 240, 240, 360, 240, 250, 250, 370, 250, 
// UG.CU..GC
200, 200, 320, 200, 240, 240, 360, 240, 200, 200, 320, 200, 140, 140, 260, 140, 
// UG.GA..GC
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 130, 310, 250, 310, 
// UG.GC..GC
120, 300, 240, 300, 120, 300, 240, 300, 80, 260, 200, 260, 120, 300, 240, 300, 
// UG.GG..GC
0, 180, 120, 180, 170, 350, 290, 350, 120, 300, 240, 300, 130, 310, 250, 310, 
// UG.GU..GC
80, 260, 200, 260, 120, 300, 240, 300, 80, 260, 200, 260, 20, 200, 140, 200, 
// UG.UA..GC
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 370, 250, 370, 150, 
// UG.UC..GC
360, 240, 360, 140, 360, 240, 360, 140, 320, 200, 320, 100, 360, 240, 360, 140, 
// UG.UG..GC
240, 120, 240, 20, 410, 290, 410, 190, 360, 240, 360, 140, 370, 250, 370, 150, 
// UG.UU..GC
320, 200, 320, 100, 360, 240, 360, 140, 320, 200, 320, 100, 260, 140, 260, 40, 
// UG.AA..UA
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UG.AC..UA
290, 290, 170, 350, 290, 290, 170, 350, 340, 340, 220, 400, 290, 290, 170, 350, 
// UG.AG..UA
170, 170, 50, 230, 370, 370, 250, 430, 290, 290, 170, 350, 360, 360, 240, 420, 
// UG.AU..UA
340, 340, 220, 400, 290, 290, 170, 350, 340, 340, 220, 400, 190, 190, 70, 250, 
// UG.CA..UA
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 360, 360, 480, 360, 
// UG.CC..UA
290, 290, 410, 290, 290, 290, 410, 290, 340, 340, 460, 340, 290, 290, 410, 290, 
// UG.CG..UA
170, 170, 290, 170, 370, 370, 490, 370, 290, 290, 410, 290, 360, 360, 480, 360, 
// UG.CU..UA
340, 340, 460, 340, 290, 290, 410, 290, 340, 340, 460, 340, 190, 190, 310, 190, 
// UG.GA..UA
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 240, 420, 360, 420, 
// UG.GC..UA
170, 350, 290, 350, 170, 350, 290, 350, 220, 400, 340, 400, 170, 350, 290, 350, 
// UG.GG..UA
50, 230, 170, 230, 250, 430, 370, 430, 170, 350, 290, 350, 240, 420, 360, 420, 
// UG.GU..UA
220, 400, 340, 400, 170, 350, 290, 350, 220, 400, 340, 400, 70, 250, 190, 250, 
// UG.UA..UA
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 480, 360, 480, 260, 
// UG.UC..UA
410, 290, 410, 190, 410, 290, 410, 190, 460, 340, 460, 240, 410, 290, 410, 190, 
// UG.UG..UA
290, 170, 290, 70, 490, 370, 490, 270, 410, 290, 410, 190, 480, 360, 480, 260, 
// UG.UU..UA
460, 340, 460, 240, 410, 290, 410, 190, 460, 340, 460, 240, 310, 190, 310, 90, 
// UG.AA..GU
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 410, 410, 290, 470, 
// UG.AC..GU
290, 290, 170, 350, 290, 290, 170, 350, 350, 350, 230, 410, 290, 290, 170, 350, 
// UG.AG..GU
170, 170, 50, 230, 410, 410, 290, 470, 290, 290, 170, 350, 410, 410, 290, 470, 
// UG.AU..GU
350, 350, 230, 410, 290, 290, 170, 350, 350, 350, 230, 410, 190, 190, 70, 250, 
// UG.CA..GU
290, 290, 410, 290, 290, 290, 410, 290, 170, 170, 290, 170, 410, 410, 530, 410, 
// UG.CC..GU
290, 290, 410, 290, 290, 290, 410, 290, 350, 350, 470, 350, 290, 290, 410, 290, 
// UG.CG..GU
170, 170, 290, 170, 410, 410, 530, 410, 290, 290, 410, 290, 410, 410, 530, 410, 
// UG.CU..GU
350, 350, 470, 350, 290, 290, 410, 290, 350, 350, 470, 350, 190, 190, 310, 190, 
// UG.GA..GU
170, 350, 290, 350, 170, 350, 290, 350, 50, 230, 170, 230, 290, 470, 410, 470, 
// UG.GC..GU
170, 350, 290, 350, 170, 350, 290, 350, 230, 410, 350, 410, 170, 350, 290, 350, 
// UG.GG..GU
50, 230, 170, 230, 290, 470, 410, 470, 170, 350, 290, 350, 290, 470, 410, 470, 
// UG.GU..GU
230, 410, 350, 410, 170, 350, 290, 350, 230, 410, 350, 410, 70, 250, 190, 250, 
// UG.UA..GU
410, 290, 410, 190, 410, 290, 410, 190, 290, 170, 290, 70, 530, 410, 530, 310, 
// UG.UC..GU
410, 290, 410, 190, 410, 290, 410, 190, 470, 350, 470, 250, 410, 290, 410, 190, 
// UG.UG..GU
290, 170, 290, 70, 530, 410, 530, 310, 410, 290, 410, 190, 530, 410, 530, 310, 
// UG.UU..GU
470, 350, 470, 250, 410, 290, 410, 190, 470, 350, 470, 250, 310, 190, 310, 90, 
// UG.AA..UG
240, 240, 120, 300, 240, 240, 120, 300, 120, 120, 0, 180, 310, 310, 190, 370, 
// UG.AC..UG
240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 240, 240, 120, 300, 
// UG.AG..UG
120, 120, 0, 180, 330, 330, 210, 390, 240, 240, 120, 300, 310, 310, 190, 370, 
// UG.AU..UG
260, 260, 140, 320, 240, 240, 120, 300, 240, 240, 120, 300, 140, 140, 20, 200, 
// UG.CA..UG
240, 240, 360, 240, 240, 240, 360, 240, 120, 120, 240, 120, 310, 310, 430, 310, 
// UG.CC..UG
240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 240, 240, 360, 240, 
// UG.CG..UG
120, 120, 240, 120, 330, 330, 450, 330, 240, 240, 360, 240, 310, 310, 430, 310, 
// UG.CU..UG
260, 260, 380, 260, 240, 240, 360, 240, 240, 240, 360, 240, 140, 140, 260, 140, 
// UG.GA..UG
120, 300, 240, 300, 120, 300, 240, 300, 0, 180, 120, 180, 190, 370, 310, 370, 
// UG.GC..UG
120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 120, 300, 240, 300, 
// UG.GG..UG
0, 180, 120, 180, 210, 390, 330, 390, 120, 300, 240, 300, 190, 370, 310, 370, 
// UG.GU..UG
140, 320, 260, 320, 120, 300, 240, 300, 120, 300, 240, 300, 20, 200, 140, 200, 
// UG.UA..UG
360, 240, 360, 140, 360, 240, 360, 140, 240, 120, 240, 20, 430, 310, 430, 210, 
// UG.UC..UG
360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 360, 240, 360, 140, 
// UG.UG..UG
240, 120, 240, 20, 450, 330, 450, 230, 360, 240, 360, 140, 430, 310, 430, 210, 
// UG.UU..UG
380, 260, 380, 160, 360, 240, 360, 140, 360, 240, 360, 140, 260, 140, 260, 40, 
// >Interior Loops 1x2
// >CG.A..AU = 5'- C A   A -3'
// >           3'- G Y X U -5'
// >Rows: X = A C G U (X constant for a row)
// >Columns: Y = A C G U (Y constant in column)
// AU.A..AU
340, 340, 220, 390, 340, 340, 220, 390, 220, 220, 100, 270, 460, 460, 340, 510, 
// AU.C..AU
340, 340, 420, 340, 340, 340, 420, 340, 400, 400, 480, 400, 340, 340, 420, 340, 
// AU.G..AU
100, 270, 220, 270, 340, 510, 460, 510, 220, 390, 340, 390, 340, 510, 460, 510, 
// AU.U..AU
470, 400, 470, 300, 410, 340, 410, 240, 470, 400, 470, 300, 310, 240, 310, 140, 
// AU.A..CG
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 360, 360, 240, 410, 
// AU.C..CG
290, 290, 370, 290, 290, 290, 370, 290, 290, 290, 370, 290, 290, 290, 370, 290, 
// AU.G..CG
50, 220, 170, 220, 260, 430, 380, 430, 170, 340, 290, 340, 240, 410, 360, 410, 
// AU.U..CG
380, 310, 380, 210, 360, 290, 360, 190, 360, 290, 360, 190, 260, 190, 260, 90, 
// AU.A..GC
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 300, 300, 180, 350, 
// AU.C..GC
290, 290, 370, 290, 290, 290, 370, 290, 250, 250, 330, 250, 290, 290, 370, 290, 
// AU.G..GC
50, 220, 170, 220, 220, 390, 340, 390, 170, 340, 290, 340, 180, 350, 300, 350, 
// AU.U..GC
320, 250, 320, 150, 360, 290, 360, 190, 320, 250, 320, 150, 260, 190, 260, 90, 
// AU.A..UA
340, 340, 220, 390, 340, 340, 220, 390, 220, 220, 100, 270, 410, 410, 290, 460, 
// AU.C..UA
340, 340, 420, 340, 340, 340, 420, 340, 390, 390, 470, 390, 340, 340, 420, 340, 
// AU.G..UA
100, 270, 220, 270, 300, 470, 420, 470, 220, 390, 340, 390, 290, 460, 410, 460, 
// AU.U..UA
460, 390, 460, 290, 410, 340, 410, 240, 460, 390, 460, 290, 310, 240, 310, 140, 
// AU.A..GU
340, 340, 220, 390, 340, 340, 220, 390, 220, 220, 100, 270, 460, 460, 340, 510, 
// AU.C..GU
340, 340, 420, 340, 340, 340, 420, 340, 400, 400, 480, 400, 340, 340, 420, 340, 
// AU.G..GU
100, 270, 220, 270, 340, 510, 460, 510, 220, 390, 340, 390, 340, 510, 460, 510, 
// AU.U..GU
470, 400, 470, 300, 410, 340, 410, 240, 470, 400, 470, 300, 310, 240, 310, 140, 
// AU.A..UG
290, 290, 170, 340, 290, 290, 170, 340, 170, 170, 50, 220, 360, 360, 240, 410, 
// AU.C..UG
290, 290, 370, 290, 290, 290, 370, 290, 290, 290, 370, 290, 290, 290, 370, 290, 
// AU.G..UG
50, 220, 170, 220, 260, 430, 380, 430, 170, 340, 290, 340, 240, 410, 360, 410, 
// AU.U..UG
380, 310, 380, 210, 360, 290, 360, 190, 360, 290, 360, 190, 260, 190, 260, 90, 
// CG.A..AU
290, 290, 170, 250, 290, 290, 170, 250, 170, 170, 50, 130, 410, 410, 290, 370, 
// CG.C..AU
290, 290, 340, 290, 290, 290, 340, 290, 350, 350, 400, 350, 290, 290, 340, 290, 
// CG.G..AU
50, 130, 170, 130, 290, 370, 410, 370, 170, 250, 290, 250, 290, 370, 410, 370, 
// CG.U..AU
360, 350, 360, 250, 300, 290, 300, 190, 360, 350, 360, 250, 200, 190, 200, 90, 
// CG.A..CG
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 310, 310, 190, 270, 
// CG.C..CG
240, 240, 290, 240, 240, 240, 290, 240, 240, 240, 290, 240, 240, 240, 290, 240, 
// CG.G..CG
0, 80, 120, 80, 210, 290, 330, 290, 120, 200, 240, 200, 190, 270, 310, 270, 
// CG.U..CG
270, 260, 270, 160, 250, 240, 250, 140, 250, 240, 250, 140, 150, 140, 150, 40, 
// CG.A..GC
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 250, 250, 130, 210, 
// CG.C..GC
240, 240, 290, 240, 240, 240, 290, 240, 200, 200, 250, 200, 240, 240, 290, 240, 
// CG.G..GC
0, 80, 120, 80, 170, 250, 290, 250, 120, 200, 240, 200, 130, 210, 250, 210, 
// CG.U..GC
210, 200, 210, 100, 250, 240, 250, 140, 210, 200, 210, 100, 150, 140, 150, 40, 
// CG.A..UA
290, 290, 170, 250, 290, 290, 170, 250, 170, 170, 50, 130, 360, 360, 240, 320, 
// CG.C..UA
290, 290, 340, 290, 290, 290, 340, 290, 340, 340, 390, 340, 290, 290, 340, 290, 
// CG.G..UA
50, 130, 170, 130, 250, 330, 370, 330, 170, 250, 290, 250, 240, 320, 360, 320, 
// CG.U..UA
350, 340, 350, 240, 300, 290, 300, 190, 350, 340, 350, 240, 200, 190, 200, 90, 
// CG.A..GU
290, 290, 170, 250, 290, 290, 170, 250, 170, 170, 50, 130, 410, 410, 290, 370, 
// CG.C..GU
290, 290, 340, 290, 290, 290, 340, 290, 350, 350, 400, 350, 290, 290, 340, 290, 
// CG.G..GU
50, 130, 170, 130, 290, 370, 410, 370, 170, 250, 290, 250, 290, 370, 410, 370, 
// CG.U..GU
360, 350, 360, 250, 300, 290, 300, 190, 360, 350, 360, 250, 200, 190, 200, 90, 
// CG.A..UG
240, 240, 120, 200, 240, 240, 120, 200, 120, 120, 0, 80, 310, 310, 190, 270, 
// CG.C..UG
240, 240, 290, 240, 240, 240, 290, 240, 240, 240, 290, 240, 240, 240, 290, 240, 
// CG.G..UG
0, 80, 120, 80, 210, 290, 330, 290, 120, 200, 240, 200, 190, 270, 310, 270, 
// CG.U..UG
270, 260, 270, 160, 250, 240, 250, 140, 250, 240, 250, 140, 150, 140, 150, 40, 
// GC.A..AU
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 410, 410, 290, 430, 
// GC.C..AU
290, 290, 380, 290, 290, 290, 380, 290, 350, 350, 440, 350, 290, 290, 380, 290, 
// GC.G..AU
50, 170, 170, 170, 290, 410, 410, 410, 170, 290, 290, 290, 290, 410, 410, 410, 
// GC.U..AU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// GC.A..CG
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GC.C..CG
240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 
// GC.G..CG
0, 120, 120, 120, 210, 330, 330, 330, 120, 240, 240, 240, 190, 310, 310, 310, 
// GC.U..CG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// GC.A..GC
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 250, 250, 130, 270, 
// GC.C..GC
240, 240, 330, 240, 240, 240, 330, 240, 200, 200, 290, 200, 240, 240, 330, 240, 
// GC.G..GC
0, 120, 120, 120, 170, 290, 290, 290, 120, 240, 240, 240, 130, 250, 250, 250, 
// GC.U..GC
270, 200, 270, 100, 310, 240, 310, 140, 270, 200, 270, 100, 210, 140, 210, 40, 
// GC.A..UA
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 360, 360, 240, 380, 
// GC.C..UA
290, 290, 380, 290, 290, 290, 380, 290, 340, 340, 430, 340, 290, 290, 380, 290, 
// GC.G..UA
50, 170, 170, 170, 250, 370, 370, 370, 170, 290, 290, 290, 240, 360, 360, 360, 
// GC.U..UA
410, 340, 410, 240, 360, 290, 360, 190, 410, 340, 410, 240, 260, 190, 260, 90, 
// GC.A..GU
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 410, 410, 290, 430, 
// GC.C..GU
290, 290, 380, 290, 290, 290, 380, 290, 350, 350, 440, 350, 290, 290, 380, 290, 
// GC.G..GU
50, 170, 170, 170, 290, 410, 410, 410, 170, 290, 290, 290, 290, 410, 410, 410, 
// GC.U..GU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// GC.A..UG
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GC.C..UG
240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 
// GC.G..UG
0, 120, 120, 120, 210, 330, 330, 330, 120, 240, 240, 240, 190, 310, 310, 310, 
// GC.U..UG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// UA.A..AU
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 460, 460, 340, 520, 
// UA.C..AU
340, 340, 460, 340, 340, 340, 460, 340, 400, 400, 520, 400, 340, 340, 460, 340, 
// UA.G..AU
100, 280, 220, 280, 340, 520, 460, 520, 220, 400, 340, 400, 340, 520, 460, 520, 
// UA.U..AU
520, 400, 520, 300, 460, 340, 460, 240, 520, 400, 520, 300, 360, 240, 360, 140, 
// UA.A..CG
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UA.C..CG
290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 
// UA.G..CG
50, 230, 170, 230, 260, 440, 380, 440, 170, 350, 290, 350, 240, 420, 360, 420, 
// UA.U..CG
430, 310, 430, 210, 410, 290, 410, 190, 410, 290, 410, 190, 310, 190, 310, 90, 
// UA.A..GC
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 300, 300, 180, 360, 
// UA.C..GC
290, 290, 410, 290, 290, 290, 410, 290, 250, 250, 370, 250, 290, 290, 410, 290, 
// UA.G..GC
50, 230, 170, 230, 220, 400, 340, 400, 170, 350, 290, 350, 180, 360, 300, 360, 
// UA.U..GC
370, 250, 370, 150, 410, 290, 410, 190, 370, 250, 370, 150, 310, 190, 310, 90, 
// UA.A..UA
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 410, 410, 290, 470, 
// UA.C..UA
340, 340, 460, 340, 340, 340, 460, 340, 390, 390, 510, 390, 340, 340, 460, 340, 
// UA.G..UA
100, 280, 220, 280, 300, 480, 420, 480, 220, 400, 340, 400, 290, 470, 410, 470, 
// UA.U..UA
510, 390, 510, 290, 460, 340, 460, 240, 510, 390, 510, 290, 360, 240, 360, 140, 
// UA.A..GU
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 460, 460, 340, 520, 
// UA.C..GU
340, 340, 460, 340, 340, 340, 460, 340, 400, 400, 520, 400, 340, 340, 460, 340, 
// UA.G..GU
100, 280, 220, 280, 340, 520, 460, 520, 220, 400, 340, 400, 340, 520, 460, 520, 
// UA.U..GU
520, 400, 520, 300, 460, 340, 460, 240, 520, 400, 520, 300, 360, 240, 360, 140, 
// UA.A..UG
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UA.C..UG
290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 
// UA.G..UG
50, 230, 170, 230, 260, 440, 380, 440, 170, 350, 290, 350, 240, 420, 360, 420, 
// UA.U..UG
430, 310, 430, 210, 410, 290, 410, 190, 410, 290, 410, 190, 310, 190, 310, 90, 
// GU.A..AU
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 410, 410, 290, 430, 
// GU.C..AU
290, 290, 380, 290, 290, 290, 380, 290, 350, 350, 440, 350, 290, 290, 380, 290, 
// GU.G..AU
50, 170, 170, 170, 290, 410, 410, 410, 170, 290, 290, 290, 290, 410, 410, 410, 
// GU.U..AU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// GU.A..CG
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GU.C..CG
240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 
// GU.G..CG
0, 120, 120, 120, 210, 330, 330, 330, 120, 240, 240, 240, 190, 310, 310, 310, 
// GU.U..CG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// GU.A..GC
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 250, 250, 130, 270, 
// GU.C..GC
240, 240, 330, 240, 240, 240, 330, 240, 200, 200, 290, 200, 240, 240, 330, 240, 
// GU.G..GC
0, 120, 120, 120, 170, 290, 290, 290, 120, 240, 240, 240, 130, 250, 250, 250, 
// GU.U..GC
270, 200, 270, 100, 310, 240, 310, 140, 270, 200, 270, 100, 210, 140, 210, 40, 
// GU.A..UA
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 360, 360, 240, 380, 
// GU.C..UA
290, 290, 380, 290, 290, 290, 380, 290, 340, 340, 430, 340, 290, 290, 380, 290, 
// GU.G..UA
50, 170, 170, 170, 250, 370, 370, 370, 170, 290, 290, 290, 240, 360, 360, 360, 
// GU.U..UA
410, 340, 410, 240, 360, 290, 360, 190, 410, 340, 410, 240, 260, 190, 260, 90, 
// GU.A..GU
290, 290, 170, 310, 290, 290, 170, 310, 170, 170, 50, 190, 410, 410, 290, 430, 
// GU.C..GU
290, 290, 380, 290, 290, 290, 380, 290, 350, 350, 440, 350, 290, 290, 380, 290, 
// GU.G..GU
50, 170, 170, 170, 290, 410, 410, 410, 170, 290, 290, 290, 290, 410, 410, 410, 
// GU.U..GU
420, 350, 420, 250, 360, 290, 360, 190, 420, 350, 420, 250, 260, 190, 260, 90, 
// GU.A..UG
240, 240, 120, 260, 240, 240, 120, 260, 120, 120, 0, 140, 310, 310, 190, 330, 
// GU.C..UG
240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 240, 240, 330, 240, 
// GU.G..UG
0, 120, 120, 120, 210, 330, 330, 330, 120, 240, 240, 240, 190, 310, 310, 310, 
// GU.U..UG
330, 260, 330, 160, 310, 240, 310, 140, 310, 240, 310, 140, 210, 140, 210, 40, 
// UG.A..AU
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 460, 460, 340, 520, 
// UG.C..AU
340, 340, 460, 340, 340, 340, 460, 340, 400, 400, 520, 400, 340, 340, 460, 340, 
// UG.G..AU
100, 280, 220, 280, 340, 520, 460, 520, 220, 400, 340, 400, 340, 520, 460, 520, 
// UG.U..AU
520, 400, 520, 300, 460, 340, 460, 240, 520, 400, 520, 300, 360, 240, 360, 140, 
// UG.A..CG
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UG.C..CG
290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 
// UG.G..CG
50, 230, 170, 230, 260, 440, 380, 440, 170, 350, 290, 350, 240, 420, 360, 420, 
// UG.U..CG
430, 310, 430, 210, 410, 290, 410, 190, 410, 290, 410, 190, 310, 190, 310, 90, 
// UG.A..GC
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 300, 300, 180, 360, 
// UG.C..GC
290, 290, 410, 290, 290, 290, 410, 290, 250, 250, 370, 250, 290, 290, 410, 290, 
// UG.G..GC
50, 230, 170, 230, 220, 400, 340, 400, 170, 350, 290, 350, 180, 360, 300, 360, 
// UG.U..GC
370, 250, 370, 150, 410, 290, 410, 190, 370, 250, 370, 150, 310, 190, 310, 90, 
// UG.A..UA
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 410, 410, 290, 470, 
// UG.C..UA
340, 340, 460, 340, 340, 340, 460, 340, 390, 390, 510, 390, 340, 340, 460, 340, 
// UG.G..UA
100, 280, 220, 280, 300, 480, 420, 480, 220, 400, 340, 400, 290, 470, 410, 470, 
// UG.U..UA
510, 390, 510, 290, 460, 340, 460, 240, 510, 390, 510, 290, 360, 240, 360, 140, 
// UG.A..GU
340, 340, 220, 400, 340, 340, 220, 400, 220, 220, 100, 280, 460, 460, 340, 520, 
// UG.C..GU
340, 340, 460, 340, 340, 340, 460, 340, 400, 400, 520, 400, 340, 340, 460, 340, 
// UG.G..GU
100, 280, 220, 280, 340, 520, 460, 520, 220, 400, 340, 400, 340, 520, 460, 520, 
// UG.U..GU
520, 400, 520, 300, 460, 340, 460, 240, 520, 400, 520, 300, 360, 240, 360, 140, 
// UG.A..UG
290, 290, 170, 350, 290, 290, 170, 350, 170, 170, 50, 230, 360, 360, 240, 420, 
// UG.C..UG
290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 290, 290, 410, 290, 
// UG.G..UG
50, 230, 170, 230, 260, 440, 380, 440, 170, 350, 290, 350, 240, 420, 360, 420, 
// UG.U..UG
430, 310, 430, 210, 410, 290, 410, 190, 410, 290, 410, 190, 310, 190, 310, 90, 
// >POLYC - Penalty for poly C hairpins.
// >First number is penalty for polyC triloop
// >Second number is "slope", i.e. penalty per C in a non triloop
// >Third number is "intercept", i.e. constant penalty for non triloops
0, 0, 0, 
// >BETA - Pseudoknot energy parameters.  B1 B2 B3 B1M B1P
// >B1 = Constant penalty for "open" pseudoknot
// >B2 = penalty per pair in pseudoknot
// >B3 = penalty per base in pseudoknot
// >B1M = constant penalty for pseudoknot in a "closed" loop
// >B1P = constant penalty for pseudoknot in a pseudoknot.
960, 10, 10, 1500, 1500, 
// >BIMOLECULAR //TINOCO, 277
409 };